Since Trump contradicts himself constantly and utters crazy things on a daily basis due to mental instability, the effect would be the same as being on the receiving end of an artillery barrage. Things around the Republican candidates and national committee would just start blowing up without warning and they'd have to do their best to survive. I would think that within a week or two, every candidate the Republicans had would be running away from Trump as fast as they could.
The only person who would enjoy it would be Trump himself. He wouldn't see anything wrong with the situation and would spend his time blaming everyone else, threatening lawsuits and calling them names. The resulting chaos would be a marvel to behold.